ELISA Substrates and Reagents
ABclonal Technology Phospho-SHP2-Y542 Rabbit pAb
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
ABclonal Technology Phospho-Beclin 1-Ser90 Rabbit pAb
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Meso Scale Discovery R-PLEX Human CEACAM-1 ASYQP
The R-PLEX Human CEACAM-1 Assay is a multiplex immunoassay kit from Meso Scale Diagnostics that allows for the simultaneous quantitative measurement of CEACAM-1 in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume This assay kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL compound calibrators diluent and wash buffer It can accurately quantify CEACAM-1 levels between 0 61 pg/mL to 2500 pg/mL
Genscript Corporation CEACAM-6/CD66c His Cynomolgu
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role in carcinogenesis and development
Cayman Chemical p38α MAPK-IN-1, Purity: ≥98%, CAS: 443913-15-3, 5 mg
A p38α MAPK inhibitor (IC50 = 5,500 nM in an HTRF assay); inhibits LPS-induced TNF-α production in THP-1 cells (EC50 = 6,200 nM); has been used in the study of p38α MAPK inhibitor binding interactions and kinetics
American Research Products Inc Rat Urokinase type Plasminogen
Rat Urokinase-type Plasminogen ActiVator Receptor PLAUR/uPAR ELISA kit from CUSABIO Detection Range 0 156 ng/mL-10 ng/mL Sensitivity 0 039 ng/mL Sample serum plasma tissue homogenates Method Sandwich
ABclonal Technology WNK1 Rabbit pAb
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.
ABclonal Technology Phospho-CDK1-T14 Rabbit pAb
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.