ELISA Substrates and Reagents
ABclonal Technology Phospho-IκBα-S36 Rabbit pAb
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
American Research Products Inc AMERICAN RESEARCH PRODUCTS INC
5000601453 BOVINE IL-1 BETA ELISPOT KIT
AdipoGen TMB dihydrochloride
Chemical. CAS 64285-73-0. Formula C16H20N2 . 2HCl. MW 240.3 . 72.9. Synthetic TMBZ is a chromogenic reagent utilized for peroxidase detection. It has been developed as an alternative to benzidine. Although the TMBZ solution is colorless, it turns bluish-green lambdamax 655 nm in the presence of hydrogen peroxide and peroxidase. The structure of this bluish-green complex is thought to be a radical form of two oxidized TMBZ molecules. This peroxidase substrate is used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays ELISA. The substrate produces a soluble end product that is pale blue in color and can be read spectrophotometrically at 370 or 620-650 nm. The TMB reaction may be stopped with 2M H2SO4 resulting in a yellow color, and read at 450nm.
Sino Biological Mouse IFN-γ ELISpot KIT (ALP) 10 Kit (96 Tests)
The kit applies for the detection of mouse IFN-γ at the cellular level by counting IFN-γ-secreting cells.
ABclonal Technology Phospho-AKT1-S473 Rabbit pAb
This gene encodes a member of the AKT serine-threonine kinase family, involved in regulating cell proliferation, survival, metabolism, and angiogenesis. AKT proteins are activated by phosphorylation via phosphoinositide 3-kinase (PI3K) and play key roles in various signaling pathways, including those involving receptor tyrosine kinases and G-protein coupled receptors. AKT activation requires phosphorylation of threonine 308 and serine 473. The PI3K/AKT pathway is crucial for tumor cell survival by inhibiting apoptosis and activating survival factors. AKT also interacts with the mTOR pathway, affecting translation initiation and is often dysregulated in cancers. Mutations in this gene are linked to various cancers, Proteus syndrome, Cowden syndrome, and other growth disorders. Multiple transcript variants exist due to alternative splicing.
Sino Biological Mouse TNF-α ELISpot Kit (ALP) 1 Kit (96 Tests)
The kit applies for the detection of mouse TNF-? at the cellular level by counting TNF-?-secreting cells.
Sino Biological Human IL-4 ELISpot Kit (ALP) 10 Kit (96 Tests)
The kit applies for the detection of human IL-4 at the cellular level by counting IL-4-secreting cells.
Sino Biological Human IFN-γ ELISpot Kit (ALP) 1 Kit (96 Tests)
The kit applies for the detection of human IFN-? at the cellular level by counting IFN-?-secreting cells.
American Research Products Inc Mouse Heat shock protein HSP 9
Mouse Heat shock protein HSP 90-beta (HSP90AB1) ELISA kit from CUSABIO Detection Range 15 6 pg/mL-1000 pg/mL Sensitivity 3 9 pg/mL Sample serum plasma tissue homogenates cell lysates Method Sandwich
ABclonal Technology Phospho-PFKFB2-S483 Rabbit pAb
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
ABclonal Technology Phospho-HSP27/HSPB1-S78 Rabbit pAb
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.